In managing a patient suspected of barbiturate ingestion, what is the best course of action to improve oxygenation?

In the scenario of managing a patient suspected of barbiturate ingestion, the best course of action to improve oxygenation is through the application of mask continuous positive airway pressure (CPAP) at 5 cm H2O. Barbiturate ingestion commonly leads to respiratory depression, which can significantly compromise oxygenation levels. The use of CPAP helps to maintain open airways and improve ventilation by preventing airway collapse and allowing for better gas exchange.

CPAP can support the patient's breathing by increasing functional residual capacity and reducing the work of breathing, which is crucial in patients with decreased respiratory drive due to central nervous system depressants like barbiturates. This intervention not only improves oxygenation but also aids in reducing the risk of atelectasis and improving overall lung function.

Applying a higher FIO2 could increase the amount of oxygen delivered, but it does not address the underlying problem of hypoventilation and may not be effective if the patient cannot adequately ventilate due to respiratory depression. Inducing vomiting poses risks, including aspiration, especially in an altered level of consciousness. Administering Narcan, while potentially useful in opioid overdose cases, is ineffective in barbiturate poisoning because of the different mechanisms and receptors involved. Thus, mask CPAP is