A patient receiving mechanical ventilation is noted to have decreased lung compliance. What is a common cause for this issue?

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Decreased lung compliance refers to a situation where the lungs become stiffer or less elastic, making it more difficult for them to expand during inhalation. This can result from various pathological conditions, but acute respiratory distress syndrome (ARDS) is particularly notable for its impact on lung compliance.

In ARDS, injury to the alveolar-capillary membrane leads to inflammation, pulmonary edema, and the accumulation of fluid in the alveoli, which impairs the normal exchange of gases and decreases lung compliance. This stiffening of the lungs is characteristic of the condition and results from the combination of fluid accumulation and inflammatory processes that ultimately cause the lungs to be less able to expand and contract effectively.

Other conditions may lead to decreased compliance as well, but ARDS specifically is known for its marked effect on lung mechanics due to its direct pathophysiological changes in the lungs. Understanding the nature of ARDS and its significant impact on lung function highlights why this condition is a common cause of decreased lung compliance in mechanically ventilated patients.

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